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Human Chorionic Gonadotropin (HCG) is a hormone produced during pregnancy by the developing placenta and is used as an early detection of pregnancy. HCG is normally detected in pregnancy blood test or urine test results. Elevated HCG levels take essential role in maintaining the corpus luteum, and hence promoting progesterone production. This is vital to sustain a life developing inside the human body [1].
In addition, HCG is often used in clinical treatments. For example, in the treatment of ovary stimulation and maintenance luteal phase treatment, HCG helps stimulate ovulation ultimately leading to luteinisation [2].
Molecular Formula: C11H19N3O6S
Molecular Weight: 321.35 g/mol
Buy HCG Products Online Slovenia for clinical research purposes only.
Source: PubChem
When purchasing HCG vial for injection you will also require items for peptide reconstitution including bacteriostatic water. Find the full range of accessories here.
Buy HCG Peptide Vial Slovenia here for laboratory research use – Available in 2000iu & 5000iu vials
Slovenia Research professionals have found that Human Chorionic Gonadotropin (HCG) operates primarily through its interaction with the luteinizing hormone/chorionic gonadotropin receptor (LHCGR), a receptor found on the surface of ovarian cells. Upon binding to this receptor, the use of HCG activates intracellular signalling pathways that promote the production of progesterone, a hormone essential for preparing the uterine lining for implantation and maintaining early pregnancy. This hormone signalling cascade is critical in sustaining the corpus luteum, which secretes progesterone during the first trimester of pregnant women.
In Slovenia fertility treatments, HCG mimics the natural surge of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) to trigger ovulation, facilitating the release of a mature egg from the ovary. This action is particularly vital in assisted reproductive technologies, such as in vitro fertilization (IVF), where precise control of ovulation timing is required [6].
Beyond its reproductive functions, the effects of HCG influence other physiological processes, including the modulation of immune responses, which help in protecting the developing embryo. Its measurement in blood or urine forms the basis of many pregnancy tests, highlighting its significance in medical diagnostics [7]. Overall, HCG’s mechanisms of action emphasize its pivotal role in reproductive health and its therapeutic potential in addressing fertility-related challenges.
Buy HCG Nasal Spray from PharmaLabGlobal Slovenia offering a convenient and painless peptide delivery to your clinical research. Peptide nasal sprays are available in 15ml or 30 ml bottles.
HCG is a hormone found in the human body primarily known for its important role in maintaining pregnancy by supporting the corpus luteum, which produces progesterone essential for sustaining the uterine lining. Not enough HCG can result in fertility problems. The supplementation of HCG is commonly used in Slovenia IVF treatment [8] as it can have the following applications:
HCG maintains the corpus luteum
Research has demonstrated that HCG peptide, also known as the Human Chorionic Gonadotropin from PharmaLabGlobal, plays a crucial role in maintaining the corpus luteum. It does this by binding to the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) located on ovarian cells. This interaction initiates intracellular signalling pathways that stimulate the production of progesterone within the human body. Progesterone is a vital hormone that stabilizes the uterine lining, creating a supportive environment for a fertilized egg to implant and grow. By ensuring continuous progesterone production, HCG helps sustain the corpus luteum during the early stages of pregnancy, which is essential for preventing miscarriage [3].
Stimulates ovulation
HCG, or Human Chorionic Gonadotropin, stimulates ovulation by mimicking the natural surge of luteinizing hormone (LH) that occurs during a woman’s menstrual period cycle. Normally, this LH surge triggers the release of a mature egg from the ovary, a process essential for natural conception. In fertility treatments, such as in vitro fertilization (IVF), HCG is used to replicate this surge, hence controlling and timing ovulation precisely. Slovenia Clinical studies have found that administering HCG induces the final maturation of the egg and its release from the follicle, readying it for fertilization. This timing is critical in assisted reproductive technologies to ensure that the egg can be retrieved or fertilized at the optimal moment, thus enhancing the chances of successful conception [9].
Enhances the luteal phase
After ovulation, a temporary endocrine structure in the ovaries called the corpus luteum produces progesterone in order to stabilize uterine lining. HCG binds to the luteinizing hormone/chorionic gonadotropin receptors on the corpus luteum, stimulating its activity and prolonging its life span. This interaction serves to ensure adequate progesterone levels are maintained, which would otherwise result in the shedding of uterine lining and make it impossible for a fertilized egg to implant and grow.
Buy HCG Pre-Mixed Peptide Pen. Pen kits and pre-mixed refill cartridges supplied by PharmaLabGlobal Slovenia for clinical research purposes.
Does HCG have any possible side effects?
There are a number of side effects associated with the use of HCG peptide therapy in addition to the usual adverse effects associated with injectable peptides including redness of the injection site. Therefore it should only be used under the guidance of healthcare professionals or pharmacies.
Is HCG used in IVF Treatment?
Yes, the HCG peptide is commonly used in IVF treatments around the world. It is normally administered to women to trigger the final maturation of eggs and stimulate ovulation. It mimicks the natural luteinizing hormone levels (LH) surge, which is crucial for the timing of egg retrieval in the IVF process.
Can HCG cause weight loss?
The ‘HCG diet’ involves taking HCG and following a very low-calorie diet, is often marketed for weight loss. However, the fat loss associated with this diet is primarily due to the severe caloric restriction, not the administration of the the amount of HCG peptide itself. Please note the FDA has not approved HCG diet products for weight loss products or the treatment of obesity, and the diet is considered ineffective and unsafe due to health risks
Can HCG help with the menopause?
Peptide therapy, including HCG, can help alleviate common menopause symptoms such as hot flashes, mood swings, and vaginal dryness by promoting hormone balance and improving overall health. These peptides can enhance sexual function, boost energy levels, and support cognitive functions due to their ability to stabilise estrogen and progesterone levels. However, it’s essential to consult with a healthcare provider before starting any new treatment or supplement to ensure it’s appropriate for your specific health needs.
Is HCG legal?
With a doctor’s prescription HCG is approved in most countries by the drug administration agency. PharmaLabGlobal suppliers high purity HCG products for clinical research use only.
[1] Kumar P, Magon N. Hormones in pregnancy. Niger Med J. 2012 Oct;53(4):179-83.
[2] Janet Choi, Johan Smitz, Luteinizing hormone and human chorionic gonadotropin: Origins of difference, Molecular and Cellular Endocrinology, Volume 383, Issues 1–2, 2014, Pages 203-213.
[3] Duncan WC. The inadequate corpus luteum. Reprod Fertil. 2021 Feb 26;2(1):C1-C7.
[4] Jiang M, Wang C, Fei X, Lin Z. Pregnancy confirmed after controlled ovarian stimulation for infertility: A case report. Medicine (Baltimore). 2021 Sep 17;100(37):e27140.
[5] Mesen TB, Young SL. Progesterone and the luteal phase: a requisite to reproduction. Obstet Gynecol Clin North Am. 2015 Mar;42(1):135-51.
[6] De Cesare R, Morenghi E, Cirillo F, Ronchetti C, Canevisio V, Persico P, Baggiani A, Sandri MT, Levi-Setti PE. The Role of hCG Triggering Progesterone Levels: A Real-World Retrospective Cohort Study of More Than 8000 IVF/ICSI Cycles. Front Endocrinol (Lausanne). 2020 Sep 23;11:547684
[7] Gnoth C, Johnson S. Strips of Hope: Accuracy of Home Pregnancy Tests and New Developments. Geburtshilfe Frauenheilkd. 2014 Jul;74(7):661-669.
[8] Matorras R, Meabe A, Mendoza R, Prieto B, Ramón O, Mugica J, Aspichueta F, Exposito A. Human chorionic gonadotropin (hCG) plasma levels at oocyte retrieval and IVF outcomes. J Assist Reprod Genet. 2012 Oct;29(10):1067-71.
[9] Hershko Klement A, Shulman A. hCG Triggering in ART: An Evolutionary Concept. Int J Mol Sci. 2017 May 17;18(5):1075.
Using HCG as PCT
The blog delves into how HCG aids in restoring natural testosterone levels and maintaining hormonal balance, making it an effective post cycle support therapy or testosterone replacement therapy.
Discovering HCG Peptide
This blog explores the Slovenia research behind possible applications of HCG peptide beyond the uses in fertility and hormone balance restoration according to research.
Revolutionising Fertility Treatment with HCG
This blog investigates HCG’s multifaceted roles highlighting its contribution to higher success rates in assisted reproductive technologies. Also discussing the promising synergy of Kisspeptin, Oxytocin, and PT-141.
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